Rational choice of modelling assumptions for simulation of blood vessel end-to-side anastomosis

Blood vessels exhibit highly nonlinear, anisotropic behaviour with numerous mechanical interactions. Since exact modelling of all involved effects would yield a computationally prohibitive procedure, practical clinical simulation tool needs to account for minimum threshold relevant factors. In this study, we analyse needed assumptions reliable the end-to-side anastomosis. The artery wall is modelled in geometrically setting as pre-stressed fibre-reinforced composite. study focuses on sensitivity analysis post-anastomosis stress fields concerning assumptions. Toward that end, set full-scale finite element simulations carried out three cases: (i) post-operational stresses are estimated and without taking residual into account, (ii) Different geometries cut recipient vessel examined, (iii) influence errors material stiffness identification field estimated. studied cases (i)–(iii) have shown substantial impact considered predictive capabilities simulation. Approaches more accurate predictions distribution outlined, quest experimental procedures made. As by-product, occurrence pseudo-aneurysm explained.